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Felix, for all his greatness, tends to settle into very predictable patterns. We all remember the "all FB in the first inning" thang when he was young but he still does it. Divish had some quotes from Astros hitters - they noted that Felix throws everything at the knees and that his changeup almost always drops out of the strike zone. So their strategy was easy - focus on the bottom half of the strike zone and don't swing at anything bendy.
We did see him start to throw his FB up in the zone in his final starts, so it's not like the M's don't know what people are doing. I love the guy as much as any Mariner player ever but Felix is just so stubborn that I'm not convinced that he's going to be willing to change.